Continuous monitoring of cortical perfusion by laser Doppler flowmetry in ventilated patients with head injury.
نویسندگان
چکیده
A method for monitoring cortical perfusion by laser Doppler flowmetry (LDF) in the neurointensive care unit is described. Out of 22 patients with head injuries, reliable and long term recordings were obtained in 16. Laser Doppler flowmetry registered changes in cortical microcirculatory flow in response to spontaneous waves of raised intracranial pressure, and to therapeutic manoeuvres that altered the cerebral perfusion pressure. Comparisons of variations in flux signal with cerebral perfusion pressure provided an indication of the autoregulatory state of the cortical microcirculation, and analysis of raw LDF data demonstrated an autoregulatory breakpoint of cerebral perfusion pressure of 58 mm Hg, below which cortical perfusion failed. Although middle cerebral artery flow velocities were generally tightly coupled with LDF signal changes, episodes of uncoupling were seen. The potential uses and limitations of LDF in the neurointensive care setting are discussed.
منابع مشابه
Evaluation of Carpal Tunnel Syndrome by Laser Doppler Flowmetry
Background:Autonomic disturbance can leads to blood flow changes that can be studied by various methods. Objective: To assess the blood flow changes in patients with severe carpal tunnel syndrome by laser Doppler flowmetry Methods:Ten patients with severe unilateral carpal tunnel syndrome confirmed by electrodiagnostic examination enrolled in this study. Patients comprised one man and nine wom...
متن کاملPerfusion of the femoral head during surgical dislocation of the hip. Monitoring by laser Doppler flowmetry.
We used laser Doppler flowmetry (LDF) with a high energy (20 mW) laser to measure perfusion of the femoral head intraoperatively in 32 hips. The surgical procedure was joint debridement requiring dislocation or subluxation of the hip. The laser probe was placed within the anterosuperior quadrant of the femoral head. Blood flow was monitored in specific positions of the hip before and after disl...
متن کاملTemporal profile of cortical perfusion and microcirculation after controlled cortical impact injury in rats.
Impaired cerebral perfusion contributes to evolving posttraumatic tissue damage. Spontaneous reversibility of reduced perfusion within the first days after injury could make a persisting impact on secondary tissue damage less likely and needs to be considered for possible therapeutic approaches. The present study was designed to characterize the temporal profile and impact of trauma severity on...
متن کاملEvaluation of a Laser Doppler System for Myocardial Perfusion Monitoring
Coronary artery bypass graft (CABG) surgery is a common treatment for patients with coronary artery disease. A potential complication of CABG is myocardial ischemia or infarction. In this thesis, a method — based on laser Doppler flowmetry (LDF) — for detection of intraand postoperative ischemia by myocardial perfusion monitoring is evaluated. LDF is sensitive to motion artifacts. In previous s...
متن کاملTwo dimensional mapping of the perfusion of the retina and optic nerve head.
AIM To present a new non-invasive method of performing a high definition topography of perfused vessels of the retina and the optic nerve head with simultaneous evaluation of blood flow. METHOD By a combination of a laser Doppler flowmeter with a scanning laser system the perfusion of the retina and the optic nerve head is visualised. The principles of measuring blood flow by laser Doppler fl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 57 11 شماره
صفحات -
تاریخ انتشار 1994